Björn Schumacher

Status: Professor (W3)
Address:

Institute for genome stability in aging and disease, CECAD Research Center
University of Cologne
Joseph-Stelzmannstr. 26
50937 Cologne / Germany

Phone: +49 221/478 84202
E-Mail: bjoern.schumacher@uni-koeln.de
Nationality: German

 

Education

1995-1998

Studies in Biology (Diplomstudiengang Biologie) Department of Biology, University of Konstanz, Germany; Intermediate Examination (Vordiplom) in Biology, University of Konstanz, 21 July 1997

1998-1999 

Visiting scholar in the Master’s program of the Department of Molecular Genetics and Microbiology, State University of New York (SUNY) at Stony Brook, USA

1999

Master of Arts Degree; Master’s Thesis ‘Regulation of Nucleotide Exchange on Ras by Inter- and Intramolecular Interactions’ with Dr. Dafna Bar-Sagi, Department of Molecular Genetics and Microbiology, SUNY Stony Brook, 30 July 1999

1999-2000

Graduate student in the PhD program in Molecular Genetics and Microbiology of the Department of Molecular Genetics and Microbiology, SUNY Stony Brook

1999-2000

PhD thesis work with Dr. Michael Hengartner and Dr. Anton Gartner, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA, on ‘DNAdamage Response in Caenorhabditis elegans

2000-2004

PhD student with Dr. Anton Gartner, Department of Cell Biology, Max Planck Institute for Biochemistry, Martinsried, Germany; PhD project: ‘DNA-damage Response in Caenorhabditis elegans

2004

PhD degree, Max Planck Institute for Biochemistry and Ludwig Maximilian University of Munich, Germany, 16 April 2004

 

Professional and Research Experience

2004-2008

Postdoctoral Fellow with Prof. Jan Hoeijmakers, Department of Genetics, Erasmus Medical Center, Rotterdam, Netherlands

2009-2013

Tenure Track Independent junior research group leader in the Cologne Excellence Cluster “Cellular Stress Responses in Aging-Associated Diseases” (CECAD) Research focus DNA damage response mechanisms in Cancer and Aging

2012-present

Scientific Coordinator of the Research Area C (DNA damage response) within the Excellence cluster CECAD

2012-present

 Coordinator of the Initial training Network on chronic DNA damage responses in ageing (FP7-ITN CodeAge)

2013-present

 Full professor (W3) and Director of the Institute for Genome Stability in ageing and disease

2014-present

 Acting Director of the CECAD Research Center

 

Scientific societies

Elected Member of the faculty council, faculty of Medicine, University of Cologne (since 2015)

Member of the German Society for Ageing Research (since 2014 President)

Member of the scientific advisory board, Frankfurter Zukunftsrat (Future Think Tank)

 

Awards and Prizes

2011-2017

 European Research Council (ERC) Starting Independent Researcher Grant

2009

Innovation Prize of the State of North-Rhine Westphalia

2005-2008

EMBO long-term postdoctoral Fellowship and Marie Curie Intra-European Fellowship (from 2006)

 

List of the five most important publications

  1. Mueller M, Castells-Roca L, Babu V, Ermolaeva MA, Müller RU, Frommolt P, Williams AB, Greiss S, Schneider JI, Benzing T, Schermer B, Schumacher B. DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage. Nat Cell Biol. 2014 Nov 24:16(12):1168–1179. doi: 10.1038/ncb3071
  2. Wolters S, Ermolaeva M, Bickel J, Fingerhut J, Khanikar J, Chan R, Schumacher B. Loss of C. elegans BRCA1 promotes genome stability during replication in smc-5 mutants. Genetics. 2014 Apr;196(4):985-99. doi: 10.1534/genetics.113.158295
  3. Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B. DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance. Nature. 2013 Sep 19;501(7467):416-20. doi: 10.1038/nature12452
  4. Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LHF, van der Horst GTJ, Brüning JC, Niessen CM, Hoeijmakers JHJ and Schumacher B. Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat Cell Biol. 2009 May;11(5):604-15.
  5. Schumacher B, Hanazawa M, Lee M, Nayak S, Volkmann K,  Hofmann R, Hengartner M, Schedl T, Gartner A. Translational Repression of C. elegans p53 by GLD-1 regulates DNA damage induced apoptosis. Cell, 11 February 2005; 120: 357-368.