Hamid Kashkar

Status: Independent Research Group Leader
Address:

CECAD Research Center and Institute for Medical Microbiology, Immunology and Hygiene (IMMIH)
University of Cologne
Joseph-Stelzmannstr. 26
50937 Cologne

Phone: +49 221/478 84091
E-Mail: h.kashkar@uni-koeln.de
Nationality: German

 

Education

1987-1991

Bachelor of science (BS), Biology, University of Orumieh/Iran

1997-2000

Dipl. Biology, Institute of Genetik, University of Cologne

2000-2002

Ph.D, Biology/Genetics, University of Cologne with “Distinction”

2008

Postdoctoral lecture qualification (“Habilitation”) in immunology, University of Cologne

 

Professional and Research Experience

2002-2005

Postdoctoral research fellow, Institute for Med. Microbiology, Immunology and Hygiene (IMMIH), University of Cologne

2005-2011 

Senior Investigator with an own research group, Institute for Med. Microbiology, Immunology and Hygiene (IMMIH), University of Cologne

2011-2013

Independent research group leader, “Career Development Award” Center for Molecular Medicine, Cologne (CMMC), University of Cologne

2014-present

Independent research group leader, CECAD Cluster of Excellence and IMMIH, University of Cologne

 

Awards and Prizes

2003

Publication award 2003, Med. Faculty, University of Cologne

2007

Publication award 2007, Med. Faculty, University of Cologne

2009

Award for the best Habilitation 2009, Med. Faculty, University of Cologne

 

Scientific Societies

Deutsche Gesellschaft für Immunologie

European Cell Death Organization (ECDO)

 

List of the five most important publications

  1. Witt A, Seeger JM, Coutelle O, Zigrino P, Broxtermann P, Andree M, Brinkmann K, Jüngst C, Schauss AC, Schüll S, Wohlleber D, Knolle P, Krönke M, Mauch C, Kashkar H. IAP antagonization induces inflammatory destruction of vascular endothelium EMBO Rep. 2015, 16:719-727

  2. Andree M, Seeger JM, Schüll S, Coutelle O, Wagner-Stippich D, Wiegmann K, Wunderlich C, Brinkmann K, Broxtermann PN, Witt A., Fritsch M, Martinelli P, Bielig H, Lamkemeyer T, Rugarli EI, Kaufmann T, Sterner-Koch A, Wunderlich, FT, Villunger A, Martins LM, Krönke M, Kufer T, Utermöhlen O, Kashkar H. BID-mediated release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO J. 2014, 33:2171-2187

  3. Coutelle O, Hornig-Do HT, Witt A, Andree M, Schiffmann LM, Liwschitz M, Seeger JM, Piekarek M, Brinkmann K, Hallek M, Krönke M, Trifunovic A, Eming SA, Wiesner RJ, Hacker UT and Kashkar H. Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing EMBO Mol. Med. 2014, 6:624-639

  4. Brinkmann K, Zigrino P, Witt A, Schell M, Ackermann L, Broxtermann PN, Schüll S, Andree M, Coutelle O, Yazdanpanah B, Seeger JM, Klubertz D, Drebber U, Hacker UT, Krönke M, Mauch C, Hoppe T, and Kashkar H. Ubiquitin C-Terminal Hydrolase-L1 Potentiates Cancer Chemosensitivity by Stabilizing NOXA. Cell Rep. 2013, 3(3):881-91.

  5. Haubert D, Gharib N, Rivero F, Wiegmann K, Hösel M, Krönke M, Kashkar H. PtdIns(4,5)P-restricted plasma membrane localization of FAN is involved in TNF-induced actin reorganization. EMBO J., 2007, 26:3308–3321.